Epigenetics: How Your Lifestyle Changes Your Genes
Your DNA sequence is fixed at conception, but how your genes are expressed changes throughout your life based on your environment, diet, stress levels, and behaviors. This is the domain of epigenetics, and it explains why identical twins with the same DNA can develop different diseases as they age. Epigenetic changes involve chemical tags that attach to your DNA or the proteins around which DNA is wrapped. These tags do not change the genetic code itself but determine which genes are active and which are silent. Lifestyle factors influence these tags in measurable ways. Regular exercise changes the epigenetic marks on genes involved in metabolism and inflammation. A diet rich in vegetables and fruits provides compounds that influence gene expression through multiple pathways. Chronic stress leaves measurable epigenetic marks on genes related to the stress response system, potentially making you more reactive to future stressors. Smoking causes widespread epigenetic changes that can partially reverse after quitting. Even meditation and mindfulness practices have been shown to influence gene expression related to inflammation. The most hopeful implication of epigenetics is that your genetic destiny is not fixed. Your daily choices matter enormously.
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